3260 papers • 126 benchmarks • 313 datasets
Single Cell RNA sequencing (scRNAseq) revolutionized our understanding of the fundamental of life sciences. The technology enables an unprecedented resolution to study heterogeneity in cell populations and their functionalities.
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This study proposes models based on the Bayesian generative approach, where protein quantification available as CITE-seq counts from the same cells are used to constrain the learning process, thus forming a semi-supervised model.
It is concluded that tokenization and data representation are essential areas of research, and new strategies are needed to mitigate the effects of imbalanced learning in single-cell foundation models.
Adding a benchmark result helps the community track progress.