1
Axiomatic Attribution for Deep Networks
3
Gradient boosting machines, a tutorial
4
Identification of antimicrobial peptides from the human gut microbiome using deep learning
5
A Deep Learning Approach to Antibiotic Discovery
6
Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry
7
Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA
8
A Multidimensional Approach to Modulating Ionizable Lipids for High-Performing and Organ-Selective mRNA Delivery.
9
AGILE Platform: A Deep Learning-Powered Approach to Accelerate LNP Development for mRNA Delivery
10
Design of experiments in the optimization of nanoparticle-based drug delivery systems.
11
A Survey on Graph Diffusion Models: Generative AI in Science for Molecule, Protein and Material
12
Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing
13
Light-Activated siRNA Endosomal Release (LASER) by Porphyrin Lipid Nanoparticles.
14
High-throughput microbial culturomics using automation and machine learning
15
De novo design of luciferases using deep learning
16
Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid‐Nanoparticle Components for Therapeutic and Vaccine Applications
17
Recent Advances in Lipid Nanoparticles for Delivery of mRNA
18
Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery
19
Catalyzing next-generation Artificial Intelligence through NeuroAI
20
Accurate de novo design of membrane-traversing macrocycles
21
The role of lipid components in lipid nanoparticles for vaccines and gene therapy
22
mRNA-based therapeutics: powerful and versatile tools to combat diseases
23
Nanodelivery of nucleic acids
24
SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis
25
RNA therapy: rich history, various applications and unlimited future prospects
26
Equivariant Diffusion for Molecule Generation in 3D
27
Effectiveness of COVID-19 vaccines against symptomatic SARS-CoV-2 infection and severe outcomes with variants of concern in Ontario
28
Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm
29
An ionizable lipid toolbox for RNA delivery
30
Chemistry of Lipid Nanoparticles for RNA Delivery.
31
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers.
32
Accelerating antibiotic discovery through artificial intelligence
33
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
34
Lipid nanoparticles for mRNA delivery
35
Acute myocarditis following Comirnaty vaccination in a healthy man with previous SARS-CoV-2 infection
36
Escaping the endosome: Assessing cellular trafficking mechanisms of non-viral vehicles.
37
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels
38
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
39
Membrane destabilizing ionizable phospholipids for organ selective mRNA delivery and CRISPR/Cas gene editing
40
Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver
41
A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo.
42
Engineering precision nanoparticles for drug delivery
43
Artificial intelligence in drug discovery and development
44
Cyclic Imines in Ugi and Ugi-Type Reactions.
45
Protein and mRNA Delivery Enabled by Cholesteryl-Based Biodegradable Lipidoid Nanoparticles.
46
A Simple Framework for Contrastive Learning of Visual Representations
47
Machine learning on DNA-encoded libraries: A new paradigm for hit-finding
48
Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017-2019.
49
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
50
Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
51
Carriers Break Barriers in Drug Delivery: Endocytosis and Endosomal Escape of Gene Delivery Vectors
52
Exploration of the nanomedicine-design space with high-throughput screening and machine learning
53
How Powerful are Graph Neural Networks?
54
Optimization of a Degradable Polymer-Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells.
55
Expanding the medicinal chemistry synthetic toolbox
56
UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction
57
Mordred: a molecular descriptor calculator
58
Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs.
59
Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
60
Degradable Lipid Nanoparticles with Predictable In Vivo siRNA Delivery Activity
61
A global double‐fluorescent Cre reporter mouse
62
Ridge Regression: Biased Estimation for Nonorthogonal Problems
63
The properties of known drugs. 1. Molecular frameworks.
64
A widely applicable set of descriptors.
65
Use of Markush structure analysis techniques for descriptor generation and clustering of large combinatorial libraries.
66
Support vector machines
67
Molecular contrastive learning of representations via graph neural networks
68
Captum: a uni fi ed and generic model inter-pretability library for PyTorch
69
a method for stochastic optimization Preprint
70
Model agnostic gen-erationofcounterfactualexplanationsformolecules
